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In SUSTAIN 6, a placebo-corrected heart rate increase of 2.75 beats per minute (bpm) was observed for semaglutide 0.5 mg, and 3.2 bpm for the 1.0 mg dosage (97)
Human risk is unknown Important limits Animal studies cannot establish safe liver effects or monitoring rules for people
Meurot C, Martin C, Sudre L, Breton J, Bougault C, Rattenbach R et al (2022) Liraglutide, a glucagon-like peptide 1 receptor agonist, exerts analgesic, anti-inflammatory and anti-degradative actions in osteoarthritis
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