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During the study, one patient died and another was hospitalized, but these events were not considered related to study participation
[7] [9] Caution is advised in individuals with renal insufficiency or those on dialysis, as impaired clearance may increase the risk of accumulation and toxicity
When Injections May Be Preferred B12 injections may be preferred when a patient has been advised that injections are suitable, when absorption is a concern, when deficiency has been confirmed and requires injection treatment, when tablets are not practical, or when a patient wants professionally administered support after a suitability check
Record the date of first vial entry and discard after 28 days regardless of remaining volume and the bacteriostatic preservation system provides a defined multi-use window, not indefinite sterility maintenance
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