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Chromatin immunoprecipitation-sequencing (ChIP-seq) results also confirmed that FXR bound to the promoters of several ferroptosis-associated genes, including FPS1, GGT6, and GSTA4
Aziz Pirani and Dr
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In addition, our results suggest a novel mechanism involving low GSH-associated AMPK activation that prevents alcohol-induced steatosis, which challenges the existing knowledge on the role of low GSH in alcoholic liver disease
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