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Abstract Recent literature shows that GLP-1 receptor agonists are highly effective for weight loss and improving metabolic and cardiovascular health, often surpassing the results of lifestyle interventions alone, such as exercise and diet modification
Water weight is caused by high sodium levels in the body and consumption of refined carbohydrates & sugar spikes insulin levels which increases sodium retention leading to increased water weight
While these findings provide mechanistic plausibility for L-carnitine's effects on IR, most evidence derives from animal or cellular models, with limited human histological validation or pathway-intervention studies
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