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CURRENTLY AVAILABLE GLP-1RA BASED THERAPIES FOR OBESITY In 1964, it was discovered that when glucose was administered orally, more insulin was secreted than when it was injected intravenously, confirming the existence of incretin, a gastrointestinal factor that promotes insulin secretion [21]
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Ethics statement The animal study was approved by Northeastern University Institutional Animal Care and Use Committee protocol assigned the number 20-0626R
