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It is important to note that whilst GLP-1 receptor agonism is well characterised in approved medicines, some mechanistic claims relating to GIP and glucagon receptor activity in humans are based on preclinical data and early clinical findings, and the relative contribution of each pathway in humans is not yet fully elucidated

It has been reported that there is no reduction in its secretion in patients with T2DM [13] but a nearly total loss of insulinotropic effect is observed, even at supraphysiological concentrations, implying the existence of GIP resistance [14]

Drug Metab Pharmacokinet

How should I store DSIP once it's mixed