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GLP-1 Medications targets appetite regulation and Phentermine works as a central nervous system stimulant
Side effects (mainly gastrointestinal) can be more pronounced at higher doses, which is why tirzepatide is titrated up slowly
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Zuo Y, Yang G, Kwon E, Gan W-B (2005b) Long-term sensory deprivation prevents dendritic spine loss in primary somatosensory cortex
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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