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Polymorphisms in the GLP1R gene, particularly the rs6923761 variant, can reduce your response to pure GLP-1 agonists like semaglutide
Wegovy (semaglutide) is an injectable prescription medicine to help with patients lose weight and keep it off
The article says tirzepatide's dual GIP and GLP-1 mechanism engages additional metabolic and appetite-regulating circuits, and may influence glucose metabolism and gastric motility in ways that differ from GLP-1 activation alone
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