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Limitations The principal limitations are related to the fact that we analyzed means from the RCTs instead of individual patient-related data
Stapp Car Crash J
To be sure, I respect that weight loss is a struggle for these patients, and I prescribe and advocate for medication to help people lose weight
A clinician may consider combination therapy when metformin alone does not meet individualized glucose goals, when weight is a major treatment factor, or when a GLP-1 receptor agonist fits the broader cardiometabolic plan
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