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Participants were randomly assigned to one of five therapies: exenatide alone, dapagliflozin alone, dual therapy of exenatide and dapagliflozin, combined dapagliflozin and metformin therapy, or the weight-loss medication phentermine/topiramate extended-release

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Mechanisms of Action Cellular Pathways Affected MT2 exerts its effects primarily through activation of melanocortin receptors, notably MC1R and MC4R

Associations of Insulin Resistance With Systolic and Diastolic Blood Pressure: A Study From the HCHS/SOL