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10.1056/NEJMoa2501006 12

however, they were not greater than levels from male Gclc L-KO mice (Fig

In 2023 the American Academy of Pediatrics (AAP) and other expert bodies began endorsing earlier consideration of pharmacotherapy: weight-loss medications are now recommended for youth aged 12 (and even younger in controlled settings) who have obesity or overweight with comorbidities, after insufficient response to intensive lifestyle therapy