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(Typical inclusion & exclusions doctors consider) Potential candidates (doctor-assessed): Adults with obesity or overweight with comorbidities (e.g., T2D, dyslipidaemia, MASLD/NAFLD, OSA), or patients with T2D needing better glycaemic and weight control despite lifestyle and first-line therapy

It reduces liver fat content, improves liver enzyme levels, and may reverse liver fibrosis, making it a promising treatment option

People with severe gastrointestinal (GI) disorders, such as gastroparesis or inflammatory bowel disease, should also avoid GLP-1 agonists due to the possibility of exacerbating GI symptoms (23)

He says the drug affects the brain and appears to remove the pleasure received from drinking alcohol