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Department of Health and Human Services, ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional/
When NNMT is inhibited: NAD+ levels rise Mitochondria become more efficient Cells burn more energy, even at rest This effect helps the body shift into a more metabolically active state, making it easier to reduce fat and preserve muscle during weight loss
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In states of obesity and aging, NNMT is often overexpressed, leading to the excessive methylation and excretion of nicotinamide
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