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The results suggested that TB-500 not only potentially enhanced the viability, angiogenesis, and migratory ability of HUVEC but possibly also promoted the expression of angiopoietin-2 (Ang2), TEK receptor tyrosine kinase 2 (tie2), vascular endothelial growth factor A (VEGFA), NOTCH1 intracellular domain (N1ICD), Notch receptor 3 (Notch3), NF-B, and phosphorylated (p)-p65 in HUVEC

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The procedure was as follows: [1] (square-cube law), [2] (square-cube law), [3] (from [1], after dividing both sides by A 1 ), [4] (from [3] , after taking the square root of both sides), [5] (from [2] , after dividing both sides by V 1 ), and [6] (after incorporating expression [4] into equation [5] )

References 1 Cosmetics / MDPI (PubMed)GHK and GHK-Cu: the human copper tripeptide, its decline with age and roles in tissue remodeling