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By elucidating the molecular interactions between microbial metabolites and host cells, we can not only uncover novel insights into the metabolic origins of PCOS but also establish a theoretical foundation for precision intervention strategies targeting microbial metabolic reprogramming

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Conjugated linoleic acid (18:2), which shares similar position and stereochemistry of its two double bonds with ESA, was a poor inducer of cell death, however, suggesting that the third conjugated double bond is required for activity