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The methodological quality of the studies was analyzed through the Jadad Scale or Oxford Quality Scoring System, a critical reading tool with 5 questions associated with clinical trial analysis, which classifies the study as of low quality if its score is below 3, and considers rigorous a randomized clinical trial with a score of 510

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Higher levels of cell apoptosis and abnormal E-cadherin expression in the urothelium are associated with inflammation in patients with interstitial cystitis/painful bladder syndrome

On innovation, R&D pipelines should be oriented toward muscle preservation, digestive support, and satiety management at lower caloric loads