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Clinical trials demonstrate average weight reductions of approximately 15% with semaglutide 2.4 mg (STEP 1 trial) and 20-22.5% with tirzepatide 10-15 mg (SURMOUNT-1 trial) over 68-72 weeks
Even as new medicines transform treatment, approximately half of Americans with employer-sponsored insurance lack coverage for obesity management medications
Pramlintide is a shorter-acting analog
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