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When to see a doctor Please seek medical advice promptly if you have any of the following after a B12 injection: Chest pain, a fast or irregular heartbeat, or breathlessness

This matters for two reasons

13% of the participants treated with the combined compound ended up discontinuing the trial, while 10% of the participants treated with semaglutide discontinued, however, none of the participants treated with cagrilintide discontinued their treatment plan indicating that cagrilintide was the most well tolerated by the study participants [2]

Cagrilintide is a synthetic long-acting amylin analogue peptide studied alongside GLP-1 pathway research