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Despite advancements in understanding MAFLD pathogenesis, therapeutic targets, and drug development, no FDA-approved treatment for MAFLD currently exists [7]

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Elevated extracellular K+ activates the Na + -K + -2Cl co-transporter (NKCC1), which facilitates Na + entry into the cell and exacerbates brain edema (Zhang et al., 2017)

Together, they are used in carefully dosed cycles to support cellular resilience and skin regeneration under medical supervision