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The molecular mechanisms primarily involve excessive activation of the unfolded protein response triggered by endoplasmic reticulum stress in granulosa cells [350], leading to caspase cascade-dependent apoptosis, as well as DNA strand breaks and membrane lipid peroxidation induced by mitochondrial electron transport chain leakage in spermatozoa [351, 352]
Abstract Pigmented lesions of the oral mucosa in children can be either exogenous or endogenous in origin
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For example, if they have type 1 diabetes , where high amounts of blood sugar can cause damage to the vagus nerve that normally instructs the stomach to empty food, Kushner said
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