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Nausea, vomiting, diarrhea, constipation, and stomach discomfort are common across the class, particularly early in treatment
The underlying mechanisms of cardiovascular and renal protection differ partially between GLP1-RAs (mainly anti-atherogenic and vascular effects) and SGLT2is (primarily systemic and intrarenal hemodynamic changes)
He highlighted the potential risks associated with discontinuing critical medications like GLP-1 RA Medications Discontinuation in diabetes management
Understanding the basic pharmacology explains why management strategies focus on gastric motility, meal composition, and dose titration
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