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The indirect effect has been reported to occur either through butyrate production, which has been reported to suppress kynurenine production (Martin-Gallausiaux et al., 2018), or through the maintenance of gut integrity that may prevent gastrointestinal disorders, such as inflammatory bowel disease and irritable bowel syndrome, which have been associated with disruption of the serotonergic signaling pathways (Gracie et al., 2019)
Similar content being viewed by others Subjects Introduction Several physiological functions, including those of the endocrine and metabolic systems, depend on G-protein-coupled receptor (GPCR) signaling 1,2,3,4,5,6
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