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The combining clue may be also the particular effect on blood vessels as the follow-up of its cytoprotection capability (Robert, 1979
Kisspeptin signalling in the hypothalamic arcuate nucleus regulates GnRH pulse generator frequency in the rat
Published in 1974 and shared with other researchers, the new RIA helped to establish that many nutrients, in particular fats, stimulated the release of GIP in the intestine but that fats only activated insulin 'when blood sugar levels were artificially raised as would be expected of a true incretin' (Marks 2020
It also stopped the transformation of blood glucose into glycogen in muscles
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