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Patients should contact their healthcare provider if they experience persistent vomiting or diarrhea that could lead to dehydration or kidney problems, or if they develop severe abdominal pain

The team then combined these genetic variants with other clinical information to predict who would experience side effects

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Gastrointestinal Effects GLP-1 medications have significant effects on the digestive system: They slow stomach emptying, increasing feelings of fullness They reduce gastric acid production They may help with inflammatory bowel diseases They enhance gut barrier protection They have anti-inflammatory effects in the digestive tract While these effects help with weight loss and blood sugar control, they can also cause side effects like nausea, vomiting, and diarrhea