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The research team stated, "We have provided direct genetic evidence that variants in the drug's target gene create differences in treatment response." They added, "Using genetic information, we can predict which drug will work best for each patient and what side effects to expect before starting treatment." In a commentary published alongside the study in Nature, Ruth J.F
Rebosio C, Balbi M, Passalacqua M, Ricciarelli R, Fedele E (2018) Presynaptic GLP-1 receptors enhance the depolarization-evoked release of glutamate and GABA in the mouse cortex and hippocampus
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