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The pathogenesis of PCOS involves oxidative stress as a fundamental factor which disrupts follicular development while inducing granulosa cell apoptosis and promoting insulin resistance ( Nrf2 is a master transcription factor that plays a key role in regulating the expression of antioxidant proteins that protect the body from oxidative damage and inflammation
easily crosses the blood-brain barrier
Table 1: Baseline cognitive function test results, April 2022
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