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Proton pump inhibitors (PPIs) and H2-receptor antagonists, used for acid reflux, reduce stomach acid production, which can impair dietary B12 absorption, though this does not directly affect injections
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[99] showed different results using a retrospective matched cohort study that utilized the TriNetX, found no increased risk of NAION or ischemic optic neuropathy among patients with T2DM or elevated BMI prescribed semaglutide over 5 years
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