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The lysates were centrifuged (10.000 g , 30 min, 4 C) and the supernatants were loaded on equilibrated Ni-NTA agarose columns (Qiagen)
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We demonstrate that mGIPR-Ab/GLP-1 peptideantibody conjugates act on CNS GIP and GLP-1 receptors via CVOs to activate neural pathways, enabling the reduction of food intake and weight loss in obese mice
[1] [2] Sermorelin: The GHRH Mimic At the heart of the peptide world, sermorelin claims a distinct spot
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