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A surge in demand for GLP-1 medications landed tirzepatide on the FDAs official drug shortage list in December 2022

The exenatide group in this study, however, showed a significant increase in the mean cardiac output by 1.2 L/min, a reduced total peripheral resistance by the mean of 120 dyns/cm 5 , and a significantly reduced urinary sodium: creatinine ratio without a significant change in the BP [39]

Several factors contributed to the pronounced spike in GLP1 spending in recent years: Perceived efficacy

Access this article Similar content being viewed by others Abbreviations AHI: apnea-hypopnea index BMI: body mass index CPAP: continuous positive airway pressure ESS: Epworth Sleepiness Scale GIP/GLP-1 receptor agonists: dual gastric inhibitory polypeptide/glucagon-like peptide-1 receptor agonists GLP-1 receptor agonists: glucagon-like peptide-1 receptor agonists ODI: oxygen desaturation index OSA: obstructive sleep apnea SGLT2 inhibitors: sodium-glucose cotransporter-2 inhibitors T2DM: type 2 diabetes mellitus REFERENCES Osman AM, Carter SG, Carberry JC, et al