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For instance, the high-lactate TME has been shown to promote processes such as invasion, angiogenesis, chemotherapy resistance, and immunosuppression

Selected References Reddy IM, Mahendrakar AS, Srikantaiah MV

Under normal physiological conditions, the rate of synthesis of GSH is determined to a large extent by two factors: (a) the activity of GCL and (b) the availability of the cysteine substrate