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Ideal candidates typically include: Body composition goals: Individuals focused on reducing body fat percentage while preserving lean muscle mass, those who have reached plateaus with diet and exercise alone, patients seeking metabolically selective approaches without growth hormones broader effects, or individuals interested in targeted fat reduction (particularly abdominal/visceral fat)

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Collectively, this study provides a solid foundation for future exploration into the impact of NNMTi-and diet-mediated changes to the gut microbiome in obese and lean populations, as well as future targets to investigate mechanistically with NNMTi treatment