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Semaglutide commonly causes nausea, vomiting, diarrhea, and constipation
The experimental inhibition of HMGB1 in myocardial ischemia or reperfusion injury, myocarditis, and cardiomyopathies have been able to attenuate disease by reducing inflammation and therefore, is protective towards the DCM phenotype
For example, Angong Niuhuang Wan inhibits the accumulation of ROS and Fe 2+ and improves mitochondrial dysfunction and BBB structural integrity by activating the PPAR/AKT/GPX4 pathway, thereby enhancing neurological function in rats with ischemic stroke and reducing cerebral infarction volume
All included patients received acetazolamide, while some received additional therapy with a GLP-1 agonist, either liraglutide or semaglutide
