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86 HP 190 MAZDUTIDE GLP-1 + Glucagon Innovent ALIASES Mazdutide, IBI362, LY3305677 CLASS GLP-1/glucagon dual receptor agonist (Innovent/Lilly) FORMULA Synthetic peptide oxyntomodulin-derived HALF-LIFE ~7 days (once-weekly) ROUTES Subcutaneous (Phase 3 clinical) MECHANISM OF ACTION Innovent Biologics dual GLP-1 and glucagon receptor agonist (IBI362), derived from oxyntomodulin lineage

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Acne was not systematically assessed or reported as an outcome measure in these pivotal studies, and it is not listed as either an indication or a common adverse reaction in UK product licences

Phase II Detoxification in the Liver Glutathione transferases (GST) conjugate GSH directly to endogenous and exogenous electrophilic compounds, including xenobiotics, carcinogens, and heavy metals