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Lancet Gastroenterol Hepatol 2023;8(4):321331

ashwagandha reliably drives it downward

GSH is synthesized in two steps: First, gamma-glutamylcysteine (-GC) is formed from glutamate and cysteine, which is the rate-limiting step in GSH production

Standard mitigation strategies include eating smaller lower-fat meals, avoiding lying down within two hours of eating, and slowing the titration schedule if symptoms are severe