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This involves enzymatic reactions that lead to the conjugation of glutathione with toxic substances, forming mercapturic acid which is then excreted from the body

Evolution of brain atrophy subtypes during aging predicts long-term cognitive decline and future Alzheimers clinical syndrome

[28], we found a 50% decrease in atrial glutathione content in patients with permanent atrial fibrillation compared to other patients with sinus rhythm, which is also consistent with the decreased incidence of postoperative atrial fibrillation observed after intravenous supplementation with the glutathione precursor, N-acetylcysteine (NAC) [37]

Overlay of the stabilized with the wild-type structure showed only minor differences in the regions where stabilizing mutations were introduced (Fig