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In aged rat models, treatment increased activity of antioxidant enzymes like superoxide dismutase (SOD), glutathione peroxidase, and glutathione-S-transferase, improving overall oxidative defense

Pain that arises with exertion and improves with rest (stable angina pattern) also suggests an ischemic heart problem

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Higher doses (1,5005,000 IU multiple times weekly) are used to restore spermatogenesis and endogenous testosterone in hypogonadotropic hypogonadism or post-anabolic-steroid recovery [5] [6]