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However, as previously mentioned, genetic mutations are often inactive until an environmental stressor impacts the expression of the gene
The half-life informs the dosing schedule and expectations about drug accumulation and clearance, but dosing decisions are based on clinical response and tolerability rather than drug levels
Exposure to GLP-1 RAs was consistently associated with significantly reduced odds of SUD cases
Oncotarget 10 , 11021118 (2019)
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