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Neagu N, Conforti C, Agozzino M, et al

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Pitfalls in the analysis of the physiological antioxidant glutathione (GSH) and its disulfide (GSSG) in biological samples: an elephant in the room

Subclinical hypothyroidism can be consistent with the above symptoms as well as a low basal body temperature (temp below 36.5 o C taken immediately upon waking, although this can also be affected by adrenal, immune and menstrual function) and the Achilles reflex test (slowed in hypothyroidism), as well as suboptimal blood results or auto-antibodies