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Novel anti-diabetic drugs such as glucagon-like peptide-1 (GLP-1) receptor agonists, sodium glucose co-transporter 2 inhibitors and dipeptidyl peptidase 4 (DPP-4) inhibitors have demonstrated some protective effects against ocular conditions, including glaucoma

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Physiol Res 67:339346 Pousti F, Ahmadi R, Mirahmadi F, Hosseinmardi N, Rohampour K (2018) Adiponectin modulates synaptic plasticity in hippocampal dentate gyrus

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Compounding Interest Why then has the FDA scheduled a hearing to discuss it

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To investigate the regulatory effects of GLP-1RAs on cholesterol metabolism in hepatocytes treated with saturated free fatty acids, cells were pretreated with 400 M PA (Sigma-Aldrich) for 24 hours, followed by treatment with 100 nM exendin-4 (Sigma-Aldrich) or liraglutide (MedChemExpress) for an additional 24 hours

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