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Chronic CNS overstimulation elevates cortisol, accelerates systemic fatigue, and erodes the deep sleep stages during which natural growth hormone peaks to preserve lean muscle tissue
The anti-inflammatory effects of this specifically target this process, reducing inflammatory damage, shortening recovery time, lowering the risk of inflammation-related complications, and preserving the function of multiple organ systems
& Atkins, W
These data underscore that even with liposomal encapsulation, anthracycline-associated cardiac risk is attenuated but not eliminated, and that more finely tuned delivery systems and better patient selection tools are needed [217]. Preclinical chitosanDOX systems offer several mechanistic advantages that align closely with these clinical needs
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