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While aspirin acts as an irreversible inhibitor of COX and directly blocks the enzyme's active site, studies have found that acetaminophen indirectly blocks COX, and that this blockade is ineffective in the presence of peroxides

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Studies have revealed that LCAC colocalizes with resident microglia/macrophages at the edge of spinal cord injury (SCI), indicating its potential involvement in the pathophysiology of SCI progression [114]

Biogenesis of p53 involves cotranslational dimerization of monomers and posttranslational dimerization of dimers