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And as compared to older diabetes medications like insulin and sulfonylureas, GLPs carry a low risk of hypoglycemia

[7] [8] GLP-1 plays a crucial role in glucose homeostasis by stimulating insulin secretion in a glucose-dependent manner, suppressing glucagon release, slowing gastric emptying, and promoting satiety through central nervous system pathways

The combination of reduced oral intake from appetite suppression and fluid losses from gastrointestinal symptoms creates a vulnerable period, especially during the first 812 weeks of therapy or following dose increases

You can either: Reconstitute in proportionally more diluent to hold concentration constant across vial sizes