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Thus, substrate profiling not only revealed the increased specificity of X(GD) proteases compared to wild-type BoNT/X and X(PC) variants but also uncovered a potential exosite interaction conserved from wild-type BoNT/X and retained in evolved gasdermin D-cleaving variants
Eamon J
"Degradable redox-responsive disulfide-based nanogel drug carriers via dithiol oxidation polymerization"
The most frequent associations in HT are APS-2 and APS-3
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