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This year, Lilly has been releasing the results of clinical studies finding that orforglipron is safe and efficacious in patients with obesity or type 2 diabetes
The FoxO transcription factor family plays a prominent role in muscle physiological regulation, especially the FoxO3a subtype, which plays a key role in muscle autophagy, metabolic regulation, and sarcopenia occurrence by regulating the expression of autophagy-related genes (such as LC3 and BNIP3) [48]
Focusing on energy metabolism, sustained ATP production is the decisive force to maintain the intracellular physiological processes
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