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Melanotan II takes a different route, truncating to the alpha-MSH 4-10 fragment and closing a lactam bridge between the Asp5 side-chain carboxyl and the Lys10 side-chain amine to give a 23-membered macrocycle (CHNO, 1024.2 g/mol, CAS 121062-08-6)
3 If A1C goals are not achieved after 3 months of dual therapy, triple therapy is subsequently recommended
Patients should discuss the evidence, potential benefits, costs, and limitations with their healthcare provider before commencing treatment
For a broader look at what the first weeks of therapy feel like, read Provns guide on what to expect during your first month on GLP-1 therapy
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