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Alterations in the expression of mucin genes, production of the mucin, and dehydration of the mucus layer are main pathogenesis in patients with COPD
Nicoletti A, Negri M, Paratore M, et al
The treated mice were administered with T1 at dose levels of 1500, 3000 and 6000 mg/kg and the control mice were administered with vehicle control (4% Tween 80 in water for injection (Brand: SIGMA, Lot No.: 44H01211) was used for vehicle control and dosing solution preparation)
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