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The FDA-approved starting dose for Ozempic and Wegovy is 0.25mg weekly, with therapeutic doses ranging from 0.5mg to 2.4mg
10.1016/0092-8674(94)90318-2 Cell 146 PopovichP
If folate deficiency is present, replacement should only be started after initiating B12 therapy to avoid worsening neurological symptoms
Candidates include survodutide, which, like tirzepatide, targets both GLP-1 and glucagon and could help treat fatty liver disease, and retatrutide, under study by Eli Lilly, which acts on three gastrointestinal hormone receptors
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