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[10] [12] Cannabis use, particularly smoking, can cause acute increases in heart rate and blood pressure
To address this, ADC linker design often incorporates self-immolative spacer s
As Professor Edison noted, this means a negative trial result may indicate lack of drug access to the brain, rather than failure of the concept itself. Dr Ivan Koychev, Clinical Associate Professor in Neuropsychiatry at Imperial, pointed out potential future developments: This is a recurring theme in Alzheimers disease therapeutics
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