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Lillys Phase 3 TRIUMPH-2 and TRIUMPH-3 trials show investigational retatrutide achieved up to 22.6% weight loss, supporting a planned FDA BLA in Q1 2027
These medicines were first developed to help people with type 2 diabetes manage blood sugar levels more effectively, but it was noticed that the medications also caused weight loss
The blockbuster weight loss medications that have transformed conversations about obesity and metabolic healthsemaglutide (Ozempic and Wegovy), tirzepatide (Zepbound or Mounjaro), and retatrutide (a newcomer on the block thats not yet FDA approved but highly anticipated for approval next year)are all peptide-based drugs
As with many popular and effective products, this has led to a number of products which claim to work like GLP-1 being advertised and sold including a raft of GLP-1 supplements
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