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Deeper Penetration: Reaches deeper tissue layers that topical formulations cannot access effectively
Immunomodulator-based combination strategies aim to both enhance host antifungal defenses and directly kill the pathogen, representing a frontier in antifungal therapy (Pirofski and Casadevall, 2006)
The overall rate of GSH synthesis is controlled by several factors including: (i) availability of the substrate mainly L-cysteine (Taylor et al., 1996)
Fer-1 increased viability to 90% of cells under Cys 2 starvation and in BSO-treated cells, and to 70% in erastin-treated cells (Fig
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